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DeCS
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Descriptor English:
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Fusaric Acid
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Descriptor Spanish:
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Ácido Fusárico
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Descriptor Portuguese:
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Ácido Fusárico
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Synonyms English:
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5 Butyl 2 pyridinedicarboxylic Acid
5-Butyl-2-pyridinedicarboxylic Acid
Acid, 5-Butyl-2-pyridinedicarboxylic
Acid, Fusaric
Calcium Fusarate
Fusarate, Calcium
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Tree Number:
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D03.066.707.200
D03.383.725.705.200
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Definition English:
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A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis. |
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Indexing Annotation English:
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/biosyn permitted if by organism
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Pharmacological Action:
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Enzyme Inhibitors
Dopamine Agents
Nucleic Acid Synthesis Inhibitors
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History Note English:
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91(75); was see under PICOLINIC ACIDS 1975-90
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Allowable Qualifiers English:
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Record Number:
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24003
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Unique Identifier:
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D005669
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Occurrence in VHL:
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Similar:
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DeCS
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